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All of the active B12 group reporting and showed reduction in severity of symptoms ranging from 31% to 70%, while the placebo controls reported fat either no change or a worsening of symptoms. Wilcoxon-Rank of .002 for the end-points of sneezing, grams nasal congestion and runny nose; and p = .005 for IgE reductions. In 1992, calories the above mentioned data from 1988 on were presented by Dr. O''Connor to the FDA. The and FDA panel acknowledged the safety of the treatment. The panel seemed to be in agreement that the statistics indicated a significant reduction in IgE and that a quantitative fat drop in symptoms was demonstrated. In 1992, Belen Anibarro, MD, studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The test was repeated after premedication with 1.5 mg of oral cyanocobalamin. In four of the five patients treated, bronchospasm did grams not develop in the second metabisulfite challenge.6

All of the active B12 group reporting and showed reduction in severity of symptoms ranging from 31% to 70%, while the placebo controls reported fat either no change or a worsening of symptoms. Wilcoxon-Rank of .002 for the end-points of sneezing, grams nasal congestion and runny nose; and p = .005 for IgE reductions. In 1992, calories the above mentioned data from 1988 on were presented by Dr. O''Connor to the FDA. The and FDA panel acknowledged the safety of the treatment. The panel seemed to be in agreement that the statistics indicated a significant reduction in IgE and that a quantitative fat drop in symptoms was demonstrated. In 1992, Belen Anibarro, MD, studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The test was repeated after premedication with 1.5 mg of oral cyanocobalamin. In four of the five patients treated, bronchospasm did grams not develop in the second metabisulfite challenge.6

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